November 29, 2023
Your liver is your most important organ for detoxification. It continuously works all day to break down and eliminate all forms of substances from the body. It has to deal with both very toxic compounds and others which are beneficial. Then decides what to do with them. Your liver is very good at deciding what needs to be kept and what needs to be removed. It functions like a massive chemical plant that manufactures certain compounds, detoxifies dangerous compounds, and directs substances all over the body for use, store or get rid of.
Your liver makes use of two pathways in order to carry out its detoxification work. Phase 1 & Phase 2 Pathways.
You can think of Phase 1 as being responsible for breaking things down and then sending the raw materials to Phase 2, which builds new substances from the raw material by adding molecules to them (this is called conjugation).
Phase 1 uses many different enzymes to break substances down that you consume. This phase is the ‘subtraction’ phase of metabolism. Where enzymes work to subtract molecules from the substances we consume and break them up into smaller more useful units in the body, just like the process of food digestion does so in the gut. Phase 1 is dependent on these enzymes, who speed up metabolism and convert fat-soluble toxins into intermediate metabolites. After the enzymes have broken down these substances, a toxic end product (metabolites) remains. Your liver then quickly works to push this toxic waste to Phase 2 pathways in order to make them safer for the body to use. Heavy metals in particular can make these liver enzymes dysfunctional.
Phase 2 is the ‘addition’ or ‘conjugation’ phase where new substances are added/conjugated to the toxic and good metabolites produced in phase 1 in order to make them easier to transport, more stable and/or more functional for the body. In Phase 2, the liver further processes the intermediate metabolites from Phase I, making them water-soluble and easier for the body to eliminate through urine or bile.
If Phase 1 or 2 Detoxification Pathways become overloaded, there will be a build up of toxins stored in the body. These toxins are fat soluble and rest themselves in ‘safe’, fatty parts of the body where they may stay for years, if not for a lifetime. Excess stored toxins in the body will show up as weight gain around the hips, thighs and leg areas.
An overburdened liver can result in symptoms of brain dysfunction, hormonal imbalances, weight gain, infertility, severe PMS, adrenal fatigue and early menopause.
Ensuring that your liver functions optimally is critical for your overall health, well being and can improve fat loss.
We often use DFH Detox AntiOx in our liver detoxification phase to help support and pull excess waste from the body.
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